User Reviews for methotrexate sodium oral

MY MOTHER WAS ON THIS MED FOR BOTH HER PSORIASIS AND PSORIATIC ARTHRITIS. SHE WAS HOSPITALIZED IN THE ICU TWICE WITH "METHOTREXATE POISONING" AND DIED THE SECOND TIME AROUND, HAVING ALSO CONTRACTED ECOLI. You already have an immune disorder if you're being prescribed this drug. These drugs suppress your immune system even more. All the pharmacists I've worked with have told me they personally would opt not to take the most meds being prescribed for these illnesses because "they are toxic".

I am in NZ and was unable to move or walk absolutely crippled with RA. They moved me onto this drug and its being brillant for holding off RA. Flare ups and side effects (hair loss, tiredness) are definitely minor to the drug usefulness. My sister also to the drug but was dizzy and nauseous so had to stop taking it. Suits some but not all, but best to try for a while as sometimes the first few weeks are the worse.

I have suffered sever side effects from the oral methotrexate and have not been able to remain on this medication.

I have had a good experience except it makes me loose my appetite to the point of my losing over 20lbs. Ive started working on eating more & maintaining as I prefer this than going to other meds.

I have a rare disease dermatomyosytis I am taking metho and have horrible sweats, even if I am doing nothing, like a hot flash only worse. I exercise, eat fairly well and I am noticing very little relief of my external symtoms of course I need to wait for blood work to see if it is helping with the muscle part of my illness. I do not think this is working for me

This medication made feel horrible. I had trouble breathing and the day after taking it could barely get out of bed. I would feel a little better after the first day but still had shortness of breath.

My husband has had psoriasis since 1999 & was diagnosed with PsA last year. He had severe (70%) coverage when he started taking MTX last year. His psoriasis was almost gone within a month. He was taken off of MTX in May due to surgery, & his psoriasis came back with a vengeance. He just restarted the MTX on Dec 7, & we can already see a 50-60% improvement in his P. As for his arthritis, he has PsA & Osteoarthritis. We have already seen a big improvement in his PsA, but of course not the OA. Because he has had kidney issues all his life, they monitor his blood work a little more often than usual (1X/month), but everything has been really good. No real complaints here.Read More Read Less

Using 20 mg once a week for about 8 years. No flare ups, only side effects are fatigue and need for naps. I can do full range of activities-bike, hike, fish, hunt, tennis and golf but not for as long duration. Very stiff after exercise or activity BUT NO PAINFUL FLAREUPS that used to leave me with useless limbs.

have taken 20mg for 5 yrs now also 500mcg folic acid 2 times a day this stops the mouth sores ,has given me much less pain, I used to live on very heavy addictive pain killers, they are not the answer , they only mask and can make you feel crazy.

I have psiotic (spelling) arthritis mostly in my wrist. Mayo client gave this to me and I have been on it for 4 weeks now. Also had cordisone shots in my wrist for the pain. That took the pain away until this medicine has time to work. The few spots of psoriasis I had left are all gone. You must have blood work done every 3 months. Also take folic acid. I have no pain anywhere.

Arthritis pain gone,Psoriasis improved. After Prednisone to get under control I started methotrexate and very satisfied.

Approx. 18,mos. ago stated with 3 tabs. 7.5mg for 20, weeks then 6,tabs 15mg for 24, weeks then 9, tabs. 22.5 for 30 weeks. Results are minimal, no noticeable side effects yet.

I have been taking this for 22 years with excellent results. I play tennis, hike, do yard work with no problems if I limit to about 4 hours a day. started with 3 pills a week, now take 6 per week. Occasional flare, maybe 2 or 3 per year, requires a couple of advil or if more severe maybe 4 day dosepack of prednisone. No side effects at this time. I do regular blood tests to check.

I was taking the 6 pills every friday, after about 4 months I started to feel a big improvement, not being woke up by pain at night etc., my MD wanted to have me start with Humira but I refused so we switched me to self-injections (ugh) to up the dose and less trauma for my stomach. Its been going ok, but this last week my husband and I found a lot of nodules on my thighs, that explains the strange pains that I've been having. So, I'll have to do some research and discuss with my MD as to a plan of action. I haven't really felt all the fatigue that some speak of, thank goodness and generally have felt so much better. Everyone is different and reacts or not differently. I have worked with physicians for many years, you must be your own best advocate, do your homework and don't be afraid to say NO to any treatment that you are unsure of!Read More Read Less

FIRST DOSAGE 4-2.5 MG TABS 7/7/13

I have taken the 17mg weekly of metho for over 18yr. mo. checks of liver, all clear. Lupus is well controlled along with prednisone, plaquenil, and anti-inflammatories. Flares are usually due to high stress or fatigue situations. In my case it has been a prayer answered for RA, Lupus & Fibro.

5mg to 8mg for flare ups, very sick at my stomach and tireness over well me

I have been on this drug for 6 weeks and increase from 10mg to 15mg. I can see no improvement with the pain. I get stomach cramps when I take the meds and then nausea for a couple of days.

I have taken this med on & off since I was in my early twentys. I tried a biologic med to treat my psoriasis but it just did not work for me. Metholtrexate has worked best for me.

This is the only drug that has worked for my mild-to-moderate seronegative RA, and I initially tried not to take it due to fear of side effects. When I was diagnosed 5 years ago, I tried anti-inflammatories, Plaquenil, sulfasalizine, Arava, and the biologics. All of those either didn't improve my symptoms or caused unbearable or scary side effects. I will not take prednisone. Eventually, I gave in and tried the methotrexate at 15mg/week, and it worked immediately. After about a year, I went down to 10mg/week, and I've been stable and virtually symptomless ever since. X-rays and scans show no permanent joint damage. I realize that I am very lucky. I initially had and still deal with hairloss and fatigue. The hairloss has lessened for me over time, though, and like other reviewers, I take my weekly dose at the beginning of the weekend to be able to deal with the fatigue. I still don't like having to take it and worry about long-term effects, but for me, the benefits definitely outweigh the negative. Read More Read Less