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Glycohemoglobin (HbA1c, A1c)

Glycohemoglobin is a blood test that checks the amount of sugar (glucose) bound to hemoglobin. Normally, only a small percentage of hemoglobin in the blood (4% to 6%) has glucose bound to it. People who have diabetes or other conditions that increase their blood glucose levels have more glycohemoglobin than normal.

The glycohemoglobin A1c test checks the long-term control of blood glucose levels in people with diabetes. Most doctors think the glycohemoglobin A1c level is the best way to check how well a person is controlling his or her diabetes.

A home blood glucose test measures the level of blood glucose only at that moment. Blood glucose levels change during the day because of diet, exercise, and the level of insulin in the blood.

It is useful for a diabetic to have information about the long-term control of blood sugar levels. The glycohemoglobin test is one blood sample every 3 to 4 months, and the test does not change with any recent changes in diet, exercise, or medicines.

Glucose binds to hemoglobin in red blood cells at a steady rate. Since red blood cells last 3 to 4 months, the glycohemoglobin A1c test shows how much glucose is in the plasma part of blood. This test shows how well your diabetes has been controlled in the last 2 to 3 months and whether your diabetes medicine needs to be changed.

The A1c level can also help your doctor see how big your risk is of developing problems from diabetes, such as kidney failure, vision problems, and leg or foot numbness. The lower your A1c level, the lower your chance for problems.

Why It Is Done

This test is done to check your treatment for diabetes.

How To Prepare

You do not need to stop eating before you have a glycohemoglobin test. This test can be done any time during the day, even after a meal.

How It Is Done

The health professional taking a sample of your blood will:

  • Wrap an elastic band around your upper arm to stop the flow of blood. This makes the veins below the band larger so it is easier to put a needle into the vein.
  • Clean the needle site with alcohol.
  • Put the needle into the vein. More than one needle stick may be needed.
  • Attach a tube to the needle to fill it with blood.
  • Remove the band from your arm when enough blood is collected.
  • Put a gauze pad or cotton ball over the needle site as the needle is removed.
  • Put pressure on the site and then put on a bandage.

How It Feels

The blood sample is taken from a vein in your arm. An elastic band is wrapped around your upper arm. It may feel tight. You may feel nothing at all from the needle, or you may feel a quick sting or pinch.

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WebMD Medical Reference from Healthwise

Last Updated: May 29, 2008
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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