What Is Diabetes Insipidus?
How Is Diabetes Insipidus Treated?
The most important part of treatment for diabetes insipidus is to drink plenty of fluids. That will replace the constant loss of water through the urine.
In central diabetes insipidus, the missing ADH can be replaced using the medication vasopressin (desmopressin or DDAVP). This is often taken as a nasal spray. An oral preparation is also available. There are also other therapies available that help enhance the action of ADH.
Nephrogenic diabetes insipidus is caused by the decreased ability of the kidneys to respond to ADH. It can be harder to treat. If nephrogenic diabetes insipidus is caused by a drug, stopping the medicine can reduce the amount of urine in people with nephrogenic diabetes insipidus. Other medicines may improve the symptoms of nephrogenic diabetes insipidus. They include indomethacin (Indocin) and, surprisingly, diuretics (hydrochlorothiazide or amiloride).
How Serious Is Diabetes Insipidus?
Diabetes insipidus does not cause kidney failure or lead to dialysis. The kidneys still do their main job of filtering the blood.
However, people with diabetes insipidus are prone to dehydration. They need to ensure constant access to drinkable fluids. Typical athletic activities and exercise are safe and promote health. But they require even more fluid replacement than usual, especially in the heat.