Diabetes: New Links to Alzheimer's
Researchers Say Diabetes Drugs Could Help Treat Alzheimer's Disease
More good news is that a class of drugs commonly used to treat diabetes
called thiazolidinediones may also influence inflammation and other brain cell
processes that may be related to Alzheimer's disease. Drugs in this class
include Avandia and Actos and they help insulin work better in the muscle and
liver to use blood sugar and also reduce sugar production in the liver.
Donald Miller, ScD from Boston University School of Public Health and
colleagues report that people with diabetes treated with these medications had
lower rates of Alzheimer's disease than counterparts taking insulin. In fact,
there were almost 20% fewer new cases of Alzheimer's among people taking
thiazolidinediones compared with people who took insulin. Similar results were
found in a separate comparison between thiazolidinediones users and people
starting Glucophage, another drug used to treat diabetes.