Diabetes Drug Actos May Also Help Prediabetes
Study Shows Actos Lowers Risk of Developing Diabetes in People With Prediabetes
Weighing Risks vs. Benefits
Study co-researcher Robert R. Henry, MD, says the findings show that targeting insulin sensitivity can have a dramatic impact on diabetes risk.
The treatment-related reduction in diabetes risk was higher than that associated with healthy changes in lifestyle in a diabetes prevention study from the National Institutes of Health.
But Henry says lifestyle intervention will remain the recommended treatment for most of his patients with prediabetes. Henry is chief of endocrinology and diabetes at the VA San Diego Healthcare System and the president of medicine and science with the American Diabetes Association.
“I might consider pioglitazone in patients who have a very high diabetes risk, but this would be a very restricted population,” he says. “As with all drug treatments, the risks and benefits have to be weighed.”