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Prediabetes - Medications

Most people with prediabetes get better results by making lifestyle changes, such as losing weight, eating a healthy diet, and getting regular exercise, than with diabetes medicine.6

But a doctor may prescribe a biguanide, usually metformin (Glucophage), because it can reduce how much glucose is made by the liver and lower insulin levels, especially in patients with polycystic ovary syndrome. In some cases a doctor may prescribe thiazolidinediones (Actos or Avandia) to lower insulin resistance. One study (the DREAM trial investigation) shows that Avandia prevents type 2 diabetes as effectively as lifestyle change but can cause you to gain weight and/or retain fluid.18 Metformin is used much more frequently.

Ask your doctor whether diet and exercise are sufficient treatment or whether you should take medicine to lower your insulin resistance.

WebMD Medical Reference from Healthwise

Last Updated: August 12, 2008
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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