Diabetes Health Center
Type 2 Diabetes: Living With Complications - What Happens
You may have started to have one or more complications from type 2 diabetes before you were diagnosed. This can happen if you had diabetes for several years before being diagnosed. If your complication progresses, it may cause serious disability or may shorten your life.
- Diabetic retinopathy can make you blind. But early treatment can reduce the risk of blindness by 90%.1 For more information, see the topic Diabetic Retinopathy.
- Large blood vessel damage (macrovascular disease) can lead to heart attack, stroke, or circulation problems in your legs. For more information, see the topics Heart Attack and Unstable Angina, Peripheral Arterial Disease of the Legs, and Stroke.
- Diabetic neuropathy can lead to a variety of problems. Peripheral neuropathy (affecting sensations and touch) along with blood vessel disease in the legs can lead to foot problems, including a deformity called Charcot foot, or osteomyelitis, a severe bone infection that may require amputation. Autonomic neuropathy (affecting internal functioning) can lead to many different problems, such as gastroparesis, hypoglycemia unawareness, and erection problems. For more information, see the topic Diabetic Neuropathy.
- Diabetic nephropathy can lead to kidney failure. But you can prevent or delay this with good control of your glucose and blood pressure. For more information, see the topic Diabetic Nephropathy.
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WebMD Medical Reference from Healthwise
Type 2 Diabetes: Living With Complications Topics
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Please see UROXATRAL full prescribing information.

