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Cold sweats, trembling hands, intense anxiety, a general sense of confusion -- no, it's not the night before final exams. These are the signs of low blood sugar or hypoglycemia. They can also be the signs of an insulin overdose, a potentially dangerous complication with diabetes.

Hypoglycemia happens to many people with diabetes. And it can sometimes be serious. Thankfully, most episodes related to insulin are avoidable if you stick with a few simple rules. WebMD takes a look at how to handle the problem of insulin overdose. Read on to learn about how to prevent it and how to treat it.

When Insulin Works too Well

Insulin stimulates the cells of the body to absorb sugar (glucose) out of the blood. It also inhibits the production of glucose by the liver. In type 1 diabetes, the body does not make insulin. In type 2 diabetes, the body is resistant to the insulin the body does make, and with time the pancreas may make less insulin. 

All people with type 1 diabetes need to take insulin injections. Many people with type 2 diabetes -- those whose blood sugar can't be controlled with oral medication, diet, and exercise -- take insulin injections.

There are several ways you can get too much insulin in your system and have a drop in your blood sugar:

  • You inject too much insulin because you have difficulty reading the syringes or vials or are unfamiliar with a new product.
  • You inject the right amount of insulin but the wrong type. For instance, you normally take 30 units of long-acting and 10 units of short-acting insulin. Injecting 30 units of short acting insulin is an easy mistake to make.
  • You inject insulin, but then didn't eat. Insulin injections should be timed with meals. Blood sugar rises after meals, but without eating, insulin lowers blood sugar levels to a potentially dangerous level.
  • You inject the right amount of insulin but inject it into an arm or leg just before exercise. Physical activity affects insulin absorption: Don't inject in an area affected by the exercise.

Symptoms of an Insulin Overdose

It doesn't matter how it happens. An insulin overdose always has the same effect: low blood sugar levels, or hypoglycemia. Symptoms of hypoglycemia include:

  • Anxiety
  • Confusion
  • Extreme hunger
  • Fatigue
  • Irritability
  • Sweating or clammy skin
  • Trembling hands

If sugar levels continue to fall during an insulin overdose, serious complications -- seizures and unconsciousness -- can occur.

Low blood sugar is defined as less than 70 mg/dL. Hypoglycemia is defined as a low blood sugar that leads to symptoms. Some people with poorly controlled diabetes can experience the symptoms of "low" blood sugar at normal blood sugar levels (70 to 120 mg/dL).

On the other hand, some people with diabetes won't experience these symptoms even at low sugar levels. For unclear reasons, some people have few warning signs when their blood sugars drop. This unawareness of low sugar is more common in people with type 1 diabetes.

Being unaware of low sugar levels means you're at higher risk for insulin problems. You may not have a warning that you sugar is low until you become too confused to correct the situation or become unconscious. Family and friends need to know what to do if the situation becomes serious.

Looking for Effective Diabetes Control?

Indications and Usage for Levemir® (insulin detemir [rDNA origin] injection):

Levemir® (insulin detemir [rDNA origin] injection) is a man-made long-acting insulin that is used to control high blood sugar in adults and children with diabetes mellitus.

Important Safety Information for Levemir® (insulin detemir [rDNA origin] injection):

Do not take Levemir® (insulin detemir [rDNA origin] injection) if your blood sugar is too low (hypoglycemia) or if you are allergic to anything in Levemir® (insulin detemir [rDNA origin] injection). If you take too much Levemir® (insulin detemir [rDNA origin] injection) your blood sugar may fall too low.

Check your blood sugar levels. Ask your health care provider what your blood sugars should be and when you should check your blood sugar levels. Alcohol, including beer and wine, may affect your blood sugar when you take Levemir® (insulin detemir [rDNA origin] injection).

Do not change the type of insulin you use unless told to do so by your health care provider. The amount of insulin you take as well as the best time for you to take your insulin may need to change if you take a different type of insulin.

Never mix Levemir® (insulin detemir [rDNA origin] injection) with other insulin products or use in an insulin pump.

Needles and Levemir® FlexPen® must not be shared.

Tell your health care provider about all medicines you take and all of your medical conditions, including if you are pregnant or breastfeeding. Your Levemir®(insulin detemir [rDNA origin] injection) dose may change if you take other medicines.

For more information, please click here for complete Levemir® (insulin detemir [rDNA origin] injection) Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Levemir® (insulin detemir [rDNA origin] injection) is a prescription medication.

If you need assistance with prescription drug costs, help may be available. Visit pparx.org or call 1-888-4PPA-NOW.

Levemir® and FlexPen® are registered trademarks of Novo Nordisk A/S.

© 2012 Novo Nordisk. All rights reserved.
0212-00007443-1 March 2012

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